TIMP4 Antibody

CATALOG NUMBER: 55-060

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
This TIMP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 48-74 amino acids from the Central region of human TIMP4.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
Predicted Molecular Weight:
26 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
TIMP4
Additional Names:
Metalloproteinase inhibitor 4, Tissue inhibitor of metalloproteinases 4, TIMP-4, TIMP4
Protein Accession Number:
Q99727
Protein Gi Number:
3915135
Ncbi Gene Id Number:
7079
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene belongs to the TIMP gene family. The proteinsencoded by this gene family are inhibitors of the matrixmetalloproteinases, a group of peptidases involved in degradationof the extracellular matrix. The secreted, netrin domain-containingprotein encoded by this gene is involved in regulation of plateletaggregation and recruitment and may play role in hormonalregulation and endometrial tissue remodeling.
Background Reference 1:
Nalpas, B., et al. Gut 59(8):1120-1126(2010)
Background Reference 2:
Bailey, S.D., et al. Diabetes Care (2010) In press :
Background Reference 3:
Wojciechowski, R., et al. Invest. Ophthalmol. Vis. Sci. (2010) In press :
Background Reference 4:
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

55-060

List Size:
400 ul

List Price:

$495.00

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