TINF2 Antibody

CATALOG NUMBER: 27-156

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TINF2.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
TINF2 antibody can be used for detection of TINF2 by ELISA at 1:1562500. TINF2 antibody can be used for detection of TINF2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. 1219 - MCF7 Cell Lysate
Predicted Molecular Weight:
50 kDa
Purification:
Antibody is purified by peptide affinity chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store TINF2 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
TINF2
Additional Names:
TINF2, TIN2, DKCA3
Protein Accession Number:
NP_001092744
Protein Gi Number:
151101266
Ncbi Gene Id Number:
26277
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
TINF2 is a component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. It plays a role in shelterin complex assembly.
Background Reference 1:
Kim, S.H., (2008) J. Cell Biol. 181 (3), 447-460.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

27-156

List Size:
100 ul

List Price:

$519.00

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