Tip60 (phospho Ser90) Antibody

CATALOG NUMBER: 79-924

Clonality:
Polyclonal
Tested Applications:
IHC
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Tip60 (phospho Ser90) antibody was raised against a peptide sequence around phosphorylation site of Serine 90 (P-G-S (p)-P-E) derived from Human Tip60.
Conjugate:
Unconjugated
Tested Applications:
IHC
Specificity:
The antibody detects endogenous levels of Tip60 only when phosphorylated at serine 90.
Predicted Molecular Weight:
58 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Isotype:
IgG
physical-state:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
KAT5
Additional Names:
HTATIP, TI60, Tat-interactive protein-60
Protein Accession Number:
NP_006379.2
Protein Gi Number:
36287069
Ncbi Gene Id Number:
10524
Background:
The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants.
Background Reference 1:
Kamine J., Virology 216:357-366(1996).
Background Reference 2:
Sheridan A.M., Mol. Cell. Biol. 21:4470-4481(2001).
Background Reference 3:
Legube G., Gene 310:161-168(2003).

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-924

List Size:
0.1 mg

List Price:

$376.00

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