TLE2 Antibody

CATALOG NUMBER: 56-312

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Mouse
Immunogen:
This TLE2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 637-665 amino acids from the C-terminal region of human TLE2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
80 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
TLE2
Additional Names:
Transducin-like enhancer protein 2, Enhancer of split groucho-like protein 2, ESG2, TLE2
Protein Accession Number:
Q04725
Protein Gi Number:
20532416
Ncbi Gene Id Number:
7089
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
TLE2 is a transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES (By similarity).
Background Reference 1:
He, Z., et al. J. Virol. 84(4):2047-2062(2010)
Background Reference 2:
Arce, L., et al. BMC Cancer 9, 159 (2009) :
Background Reference 3:
Higa, L.A., et al. Nat. Cell Biol. 8(11):1277-1283(2006)
Background Reference 4:
Javed, A., et al. J. Cell. Sci. 113 (PT 12), 2221-2231 (2000) :

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

56-312

List Size:
400 ul

List Price:

$495.00

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