Start Your Project

🛍️Explore our Promotions page to discover current deals, limited-time offers, and more!🌟

TLR Detection Set

CATALOG NUMBER: PSI-1806

Clonality:
Polyclonal
Tested Applications:
ICC, IF, IHC, WB
Species Reactivity:
Human
Specifications
Species Reactivity:
Human
Immunogen:
Rabbit polyclonal antibodies were raised against peptides corresponding to amino acid sequences from each of the corresponding proteins.
Tested Applications:
ICC, IF, IHC, WB
Set Contents:
TLR1 Antibody (NT), Cat. No. 3639 (50 μg)

TLR2 Antibody (NT), Cat. No. 3135 (50 μg)

TLR3 Antibody (CT), Cat. No. 3643 (50 μg)

TLR4 Antibody (NT), Cat. No. 3141 (50 μg)

TLR5 Antibody (CT), Cat. No. 3649 (50 μg)

TLR6 Antibody (IN), Cat. No. 3653 (50 μg)

TLR7 Antibody (IN), Cat. No. 3269 (50 μg)

TLR8 Antibody (IN), Cat. No. 3281 (50 μg)

TLR9 Antibody (IN), Cat. No. 3739 (50 μg)

TLR10 Antibody (IN), Cat. No. 3275 (50 μg)
Purification:
Antibodies are supplied as affinity chromatography purified IgG.
Clonality:
Polyclonal
physical-state:
Liquid
Buffer:
PBS containing 0.02% sodium azide.
Concentration:
Antibody 1 mg/mL
Storage Conditions:
Stable at 4°C for three months, store at -20°C for up to one year.
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The TLRs act through adaptor molecules to activate various kinases and transcription factors so the organism can respond to potential infection. These adaptor molecules include MyD88, TIRAP, TIRP, TOLLIP, and TRIF. These molecules interact with and activate the IL-1R-associated kinase (IRAK) family, which then activates TNF receptor associated factor (TRAF)-6, and ultimately leads to the activation of NF-κB. While most TLRs utilize more than one adaptor, certain adaptor molecules are essential for individual TLR signaling, e.g., TLR4 signaling is dependent on TIRP expression.

For images please see PDF data sheet
Background Reference 1:
Takeda K, Kaisho T, and Akira S. Toll-like receptors. Annu. Rev. Immunol. 2003; 21:335-76.
Background Reference 2:
Janeway CA Jr. and Medzhitov R. Innate immune recognition. Annu. Rev. Immunol. 2002; 20:197-216.
Background Reference 3:
McGettrick AF and O’Neill LAJ. The expanding family of MyD88-like adaptors in Toll-like receptor signal transduction. Mol. Imm. 2004; 41:577-82.
Set Contents:
TLR1 Antibody (NT), Cat. No. 3639 (50 μg)

TLR2 Antibody (NT), Cat. No. 3135 (50 μg)

TLR3 Antibody (CT), Cat. No. 3643 (50 μg)

TLR4 Antibody (NT), Cat. No. 3141 (50 μg)

TLR5 Antibody (CT), Cat. No. 3649 (50 μg)

TLR6 Antibody (IN), Cat. No. 3653 (50 μg)

TLR7 Antibody (IN), Cat. No. 3269 (50 μg)

TLR8 Antibody (IN), Cat. No. 3281 (50 μg)

TLR9 Antibody (IN), Cat. No. 3739 (50 μg)

TLR10 Antibody (IN), Cat. No. 3275 (50 μg)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

PSI-1806

List Size:
1 Set

List Price:

$1,689.00

Out of stock

Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

$35 Dry Ice Shipment fee may be required on some items.

Note: Online orders only accepted for shipment within the USA. Click here for the list of international distributors.

Customize your order

Bulk Pricing Available

Custom Formulations: azide free, endotoxin testing & endotoxin removal.

Pair your antibody with a Lysate, Peptide, Control, & /OR Secondary Antibody.

Contact our Customer Care Team for more information

Custom Antibody Services

Speak to one of our custom antibody specialists to discuss your next custom antibody project.

New & Featured Products

HIV-1 p24 Antibody [9D2F6] (HRP)
HIV-1 p24 Antibody [9D2F6] (HRP)

CATALOG NUMBER: PM-7369-HRP

HIV-1 p24 Antibody [9D2F6] (biotin)
HIV-1 p24 Antibody [9D2F6] (biotin)

CATALOG NUMBER: PM-7369-biotin

HIV-1 p24 Antibody [9D2F6]
HIV-1 p24 Antibody [9D2F6]

CATALOG NUMBER: PM-7369