TLR2 Antibody

CATALOG NUMBER: XW-7622

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Chicken
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Chicken
Species Reactivity:
Human, Mouse, Rat
Immunogen:
215-410
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
TLR2 antibody can be used for the detection of TLR2 by Western blot, may also work for IHC and ICC.
Predicted Molecular Weight:
89.8 kDa (calculated)
Purification:
Antigen affinity-purified
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Phosphate-Buffered Saline. No preservatives added.
Concentration:
1 mg/mL
Storage Conditions:
TLR2 antibody can be stored at 4°C for short term (weeks). Long term storage should be at -20°C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
TLR2
Additional Names:
TIL4, Toll-like receptor 2, TIL4, CD282,
Protein Accession Number:
NP_003255.2
Protein Gi Number:
19718734
Ncbi Gene Id Number:
7097
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Toll-like receptor 2; toll/interleukin 1 receptor-like 4 [Homo sapiens]. This protein is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. TLR2 gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-κB.
Background Reference 1:
Aliprantis, A. O., Yang, R. -B., Mark, M. R., Suggett, S., Devaux, B., Radolf, J. D., Klimpel, G. R., Godowski, P., Zychlinsky, A. Cell activation and apoptosis by bacterial lipoproteins through toll-like receptor-2. Science 285: 736-739, 1999.

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

XW-7622

List Size:
0.05 mg

List Price:

$585.00

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