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Antibody used in WB on Human HepG2 at 1.25 ug/ml.
Antibody used in WB on Human HepG2 at 1.25 ug/ml.

TNFRSF11B Antibody

CATALOG NUMBER: 31-004

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TNFRSF11B.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
TNFRSF11B antibody can be used for detection of TNFRSF11B by ELISA at 1:312500. TNFRSF11B antibody can be used for detection of TNFRSF11B by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. 1211 - HepG2 Cell Lysate
Predicted Molecular Weight:
46 kDa
Purification:
Antibody is purified by protein A chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store TNFRSF11B antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
TNFRSF11B
Additional Names:
TNFRSF11B, OPG, TR1, OCIF
Protein Accession Number:
NP_002537
Protein Gi Number:
148743793
Ncbi Gene Id Number:
4982
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
TNFRSF11B is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand (TNFSF11/OPGL), both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.
Background Reference 1:
Cross, S.S., et al., (2006) Int. J. Cancer 118 (8), 1901-1908.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

31-004

List Size:
100 ul

List Price:

$473.00

Datasheet
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