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Antibody used in WB on Human Muscle at 0.2-1 ug/ml.
Antibody used in WB on Human Muscle at 0.2-1 ug/ml.

TNFSF12 Antibody

CATALOG NUMBER: 31-142

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TNFSF12.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
TNFSF12 antibody can be used for detection of TNFSF12 by ELISA at 1:12500. TNFSF12 antibody can be used for detection of TNFSF12 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. XBL-10413 - Fetal Skeletal Muscle Tissue Lysate
Predicted Molecular Weight:
27 kDa, 37 kDa
Purification:
Antibody is purified by peptide affinity chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store TNFSF12 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
TNFSF12
Additional Names:
TNFSF12, APO3L, DR3LG, TWEAK
Protein Accession Number:
NP_003800
Protein Gi Number:
4507597
Ncbi Gene Id Number:
8742
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
TNFSF12 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Background Reference 1:
Jin, L., et al., (2004) J. Invest. Dermatol. 122 (5), 1175-1179.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

31-142

List Size:
100 ul

List Price:

$519.00

Datasheet
Shipping Info

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