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Western blot analysis in A549 cell line lysates (35ug/lane).
Western blot analysis in A549 cell line lysates (35ug/lane).

TNFSF14 Antibody

CATALOG NUMBER: 57-843

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This TNFSF14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-94 amino acids from the Central region of human TNFSF14.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
26 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
TNFSF14
Additional Names:
Tumor necrosis factor ligand superfamily member 14, Herpes virus entry mediator ligand, HVEM-L, Herpesvirus entry mediator ligand, CD258, Tumor necrosis factor ligand superfamily member 14, membrane form, Tumor necrosis factor ligand superfamily member 14, soluble form, TNFSF14, HVEML, LIGHT
Protein Accession Number:
O43557
Ncbi Gene Id Number:
8740
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is a member of the tumornecrosis factor (TNF) ligand family. This protein is a ligand forTNFRSF14, which is a member of the tumor necrosis factor receptorsuperfamily, and which is also known as a herpesvirus entrymediator (HVEM). This protein may function as a costimulatoryfactor for the activation of lymphoid cells and as a deterrent toinfection by herpesvirus. This protein has been shown to stimulatethe proliferation of T cells, and trigger apoptosis of varioustumor cells. This protein is also reported to prevent tumornecrosis factor alpha mediated apoptosis in primary hepatocyte. Twoalternatively spliced transcript variant encoding distinct isoformshave been reported.
Background Reference 1:
Stiles, K.M., et al. J. Virol. 84(22):11646-11660(2010)
Background Reference 2:
Jin, H.R., et al. Biochem. Biophys. Res. Commun. 400(4):581-586(2010)
Background Reference 3:
Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
Background Reference 4:
Cheung, T.C., et al. J. Immunol. 185(3):1949-1958(2010)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-843

List Size:
400 ul

List Price:

$495.00

Datasheet
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