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TNFSF18 Recombinant Protein

CATALOG NUMBER: 40-313

Specifications
source-species:
E. coli
Species:
Human
source-species:
E. coli
Recombinant Protein Sequence:
ETAKEPCMAK FGPLPSKWQM ASSEPPCVNK VSDWKLEILQ NGLYLIYGQV APNANYNDVA PFEVRLYKNK DMIQTLTNKS KIQNVGGTYE LHVGDTIDLI FNSEHQVLKN NTYWGIILLA NPQFI
Biological Activity:
Biological activity was determined by its ability to stimulate IL - 8 production by human PBMC using a concentration range of 1.0 - 10.0 ng/mL. Note: Results may vary with PBMC donors.
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μg (1EU/μg).
physical-state:
Lyophilized
Storage Conditions:
The lyophilized TNFSF18 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted TNFSF18 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing TNFSF18 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Ncbi Official Symbol:
TNFSF18
Additional Names:
TL6, AITRL, GITRL, hGITRL, TL6, UNQ149/PRO175, Tumor necrosis factor ligand superfamily member 18, Activation-inducible TNF-related ligand
Protein Accession Number:
NP_005083.2
Protein Gi Number:
157419142
Ncbi Gene Id Number:
8995
Background:
AITRL, a member of the TNF superfamily, is expressed in endothelial cells, and signals through the AITR receptor. AITRL regulates T-cell proliferation and survival, and effectuates the interaction between T lymphocytes and endothelial cells. The AITRL gene codes for a type II transmembrane protein comprised of 177 amino acids, including a 28 amino acid cytoplasmic region, a 21 amino acid transmembrane domain and a 128 amino acid extracellular domain. Recombinant human soluble AITRL is a 14.3 kDa protein, containing 126 amino acid residues corresponding to the extracellular domain of AITRL.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

40-313

List Size:
0.005 mg, 0.02 mg

List Price:

Price range: $199.00 through $305.00

Datasheet
Shipping Info

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