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Western blot analysis in mouse stomach tissue lysates (35ug/lane).
Western blot analysis in mouse stomach tissue lysates (35ug/lane).

TNNI3 Antibody

CATALOG NUMBER: 59-004

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
This TNNI3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 86-114 amino acids from the Central region of human TNNI3.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
24 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
TNNI3
Additional Names:
Troponin I, cardiac muscle, Cardiac troponin I, TNNI3, TNNC1
Protein Accession Number:
P19429
Protein Gi Number:
136213
Ncbi Gene Id Number:
7137
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Troponin I (TnI), along with troponin T (TnT) and troponinC (TnC), is one of 3 subunits that form the troponin complex of thethin filaments of striated muscle. TnI is the inhibitory subunit;blocking actin-myosin interactions and thereby mediating striatedmuscle relaxation. The TnI subfamily contains three genes:TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, andTnI-cardiac. This gene encodes the TnI-cardiac protein and isexclusively expressed in cardiac muscle tissues. Mutations in thisgene cause familial hypertrophic cardiomyopathy type 7 (CMH7) andfamilial restrictive cardiomyopathy (RCM).
Background Reference 1:
Millat, G., et al. Clin. Chim. Acta 411 (23-24), 1983-1991 (2010) :
Background Reference 2:
Murakami, C., et al. Leg Med (Tokyo) 12(6):280-283(2010)
Background Reference 3:
Millat, G., et al. EurMed Genet 53(5):261-267(2010)
Background Reference 4:
Di Chiara, A., et al.Cardiovasc Med (Hagerstown) 11(8):587-592(2010)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-004

List Size:
400 ul

List Price:

$495.00

Datasheet
Shipping Info

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