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Western blot analysis in T47D cell line lysates (35ug/lane).
Western blot analysis in T47D cell line lysates (35ug/lane).

TP53BP2 Antibody

CATALOG NUMBER: 58-427

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This TP53BP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 93-122 amino acids from the N-terminal region of human TP53BP2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
126 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
TP53BP2
Additional Names:
Apoptosis-stimulating of p53 protein 2, Bcl2-binding protein, Bbp, Renal carcinoma antigen NY-REN-51, Tumor suppressor p53-binding protein 2, 53BP2, p53-binding protein 2, p53BP2, TP53BP2, ASPP2, BBP
Protein Accession Number:
Q13625
Protein Gi Number:
33860140
Ncbi Gene Id Number:
7159
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
TP53BP2 is a member of the ASPP(apoptosis-stimulating protein of p53) family of p53 interactingproteins. The protein contains four ankyrin repeats and an SH3domain involved in protein-protein interactions. It is localized tothe perinuclear region of the cytoplasm, and regulates apoptosisand cell growth through interactions with other regulatorymolecules including members of the p53 family. Multiple transcriptvariants encoding different isoforms have been found for this gene.
Background Reference 1:
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Background Reference 2:
Zhao, J., et al. Hepatology 51(1):142-153(2010)
Background Reference 3:
Hirata, H., et al. J. Urol. 182(2):721-727(2009)
Background Reference 4:
Kweekel, D.M., et al. Br. J. Cancer 101(2):357-362(2009)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-427

List Size:
400 ul

List Price:

$495.00

Datasheet
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