TPBG Antibody

CATALOG NUMBER: 58-957

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This TPBG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 169-197 amino acids from the Central region of human TPBG.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
46 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
TPBG
Additional Names:
Trophoblast glycoprotein, 5T4 oncofetal antigen, 5T4 oncofetal trophoblast glycoprotein, 5T4 oncotrophoblast glycoprotein, M6P1, Wnt-activated inhibitory factor 1, WAIF1, TPBG, 5T4
Protein Accession Number:
Q13641
Protein Gi Number:
73621980
Ncbi Gene Id Number:
7162
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a leucine-rich transmembraneglycoprotein that may be involved in cell adhesion. The encodedprotein is an oncofetal antigen that is specific to trophoblastcells. In adults this protein is highly expressed in many tumorcells and is associated with poor clinical outcome in numerouscancers. Alternate splicing in the 5' UTR results in multipletranscript variants that encode the same protein. [provided byRefSeq].
Background Reference 1:
Elkord, E., et al. J. Immunother. 31(9):820-829(2008)
Background Reference 2:
Shingler, W.H., et al. Int. Immunol. 20(8):1057-1066(2008)
Background Reference 3:
Okazaki, S., et al. Obstet Gynecol 110(5):1130-1136(2007)
Background Reference 4:
Ward, C.M., et al. Exp. Cell Res. 312(10):1713-1726(2006)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-957

List Size:
400 ul

List Price:

$495.00

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