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Western blot analysis of extracts from HepG2 cells using TPH2 (Phospho-Ser19) Antibody. The lane on the right is treated with the antigen-specific peptide.
Western blot analysis of extracts from HepG2 cells using TPH2 (Phospho-Ser19) Antibody. The lane on the right is treated with the antigen-specific peptide.

TPH2 (phospho Ser19) Antibody

CATALOG NUMBER: 79-937

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
TPH2 (phospho Ser19) antibody was raised against a peptide sequence around phosphorylation site of Serine 19 (G-F-S (p)-L-D) derived from Human TPH2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
Western Blot: 1:500~1:1000
Specificity:
The antibody detects endogenous levels of TPH2 only when phosphorylated at serine 19.
Predicted Molecular Weight:
56 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Isotype:
IgG
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
TPH2
Additional Names:
ADHD7, NTPH, TPH2
Protein Accession Number:
NP_775489.2
Protein Gi Number:
31795563
Ncbi Gene Id Number:
121278
Background:
This gene encodes a member of the pterin-dependent aromatic acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. The human genome contains two related tryptophan hydroxylases, one on chromosome 11p15-p14 and one on chromosome 12q21. This gene is expressed predominantly in the brain stem. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression.
Background Reference 1:
Walther D.J., Science 299:76-76(2003).
Background Reference 2:
Scherer S.E., Nature 440:346-351(2006).

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-937

List Size:
0.1 mg

List Price:

$376.00

Datasheet
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