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Western blot analysis in HepG2 cell line lysates (35ug/lane).
Western blot analysis in HepG2 cell line lysates (35ug/lane).

TRAF4 Antibody

CATALOG NUMBER: 58-237

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This TRAF4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 427-455 amino acids from the C-terminal region of human TRAF4.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
54 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
TRAF4
Additional Names:
TNF receptor-associated factor 4, Cysteine-rich domain associated with RING and Traf domains protein 1, Metastatic lymph node gene 62 protein, MLN 62, RING finger protein 83, TRAF4, CART1, MLN62, RNF83
Protein Accession Number:
Q9BUZ4
Protein Gi Number:
30580636
Ncbi Gene Id Number:
9618
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a member of the TNF receptor associatedfactor (TRAF) family. TRAF proteins are associated with, andmediate signal transduction from members of the TNF receptorsuperfamily. The encoded protein has been shown to interact withneurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTRinduced cell death and NF-kappa B activation. This protein has beenfound to bind to p47phox, a cytosolic regulatory factor included ina multi-protein complex known as NAD(P)H oxidase. This proteinthus, is thought to be involved in the oxidative activation ofMAPK8/JNK. Alternatively spliced transcript variants have beenobserved but the full-length nature of only one has beendetermined.
Background Reference 1:
Li, S., et al. Mol. Cell. Biochem. 338 (1-2), 11-17 (2010) :
Background Reference 2:
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Background Reference 3:
Segat, L., et al. Vaccine 28(10):2201-2206(2010)
Background Reference 4:
Albers, H.M., et al. Ann. Rheum. Dis. 67(11):1578-1580(2008)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-237

List Size:
400 ul

List Price:

$495.00

Datasheet
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