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The purity of rh TTR / Transthyretin was determined by DTT-reduced (+) SDS-PAGE and staining overnight with Coomassie Blue.
The purity of rh TTR / Transthyretin was determined by DTT-reduced (+) SDS-PAGE and staining overnight with Coomassie Blue.

Transthyretin Recombinant Protein

CATALOG NUMBER: 96-756

Tested Applications:
WB
Specifications
source-species:
HEK293 cells
Species:
Human
source-species:
HEK293 cells
Recombinant Protein Sequence:
Gly 21 - Glu 147
Fusion Tag:
His Tag
Tested Applications:
WB
Application Note:
This recombinant protein can be used for WB. For research use only.
Predicted Molecular Weight:
14.6 kDa
Biological Activity:
Measured by its ability to bind biotinylated human RBP4 in a functional ELISA.
Purity:
>95% as determined by SDS-PAGE.
physical-state:
Lyophilized
Buffer:
PBS, pH7.4
Storage Conditions:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Ncbi Official Symbol:
TTR
Additional Names:
Transthyretin, TTR, Prealbumin, TBPA, ATTR, PALB, CTS, CTS1, HsT2651
Protein Accession Number:
NP_000362
Ncbi Gene Id Number:
7276
Background:
Transthyretin (TTR) is also known as Prealbumin, ATTR, TBPA, PALB, which belongs to the transthyretin family. Transthyretin / TTR is a serum and cerebrospinal fluid carrier of the thyroid hormone thyroxine (T4) and retinol-binding protein bound to retinol. In cerebrospinal fluid TTR is the primary carrier of T4. TTR also acts as a carrier of retinol (vitamin A) through its association with retinol-binding protein (RBP) in the blood and the CSF. Less than 1% of TTR's T4 binding sites are occupied in blood. TTR misfolding and aggregation is known to be associated with the amyloid diseases.
Background Reference 1:
Getz R.K., et al., 1999, Exp. Eye Res. 68:629-636.
Background Reference 2:
Herbert J., et al., 1986, Neurology 36:900-911.
Background Reference 3:
Mita S., et al., 1984, Biochem. Biophys. Res. Commun. 124:558-564.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

96-756

List Size:
0.1 mg

List Price:

$463.00

Datasheet
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