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Trefoil Factor 2 Recombinant Protein

CATALOG NUMBER: 40-291

Specifications
source-species:
E. coli
Species:
Human
source-species:
E. coli
Recombinant Protein Sequence:
EKPSPCQCSR LSPHNRTNCG FPGITSDQCF DNGCCFDSSV TGVPWCFHPL PKQESDQCVM EVSDRRNCGY PGISPEECAS RKCCFSNFIF EVPWCFFPKS VEDCHY
Biological Activity:
Assay 1: Biological activity was determined by its ability to chemoattract human monocytes using a concentration range of 1.0 - 10.0 μg/mL.

Assay 2: Biological activity was determined by its ability to chemoattract human MCF - 7 cells using a concentration range of 1.0 - 10.0 ng/mL.
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μg (1EU/μg).
physical-state:
Lyophilized
Storage Conditions:
The lyophilized Trefoil Factor 2 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted Trefoil Factor 2 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing Trefoil Factor 2 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Ncbi Official Symbol:
TFF2
Additional Names:
SP, SML1, Trefoil factor 2, Spasmolysin, SP
Protein Accession Number:
NP_005414.1
Protein Gi Number:
4885629
Ncbi Gene Id Number:
7032
Background:
The Trefoil Factor peptides (TFF1, TFF2 and TFF3) are expressed in the gastrointestinal tract, and appear to play an important role in intestinal mucosal defense and repair. TFF2 has been shown to inhibit gastrointestinal motility and gastric acid secretion. Recent data suggests a potential role for TFF2 in acute and chronic asthma (Nikolaidis, N.M. et al. Am. Journal Respir. Cell Mol. Biol. (2003) 4: 458-464). Recombinant human TFF2 is a 12.0 kDa polypeptide of 106 amino acid residues, which includes a 40-amino acid trefoil motif containing three conserved intramolecular disulfide bonds.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

40-291

List Size:
0.005 mg, 0.02 mg

List Price:

Price range: $199.00 through $305.00

Datasheet
Shipping Info

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