TREM2 Antibody

CATALOG NUMBER: 61-940

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This TREM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-50 amino acids from the N-terminal region of human TREM2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
25 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
TREM2
Additional Names:
Triggering receptor expressed on myeloid cells 2, TREM-2, Triggering receptor expressed on monocytes 2, TREM2
Protein Accession Number:
Q9NZC2
Protein Gi Number:
50401689
Ncbi Gene Id Number:
54209
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
TREM2 is a membrane proteinthat forms a receptor signaling complex with TYROBP. The encodedprotein may be involved in chronic inflammation by triggering theproduction of constitutive inflammatory cytokines. Defects in thisgene are a cause of polycystic lipomembranous osteodysplasia withsclerosing leukoencephalopathy (PLOSL).
Background Reference 1:
Stefano, L., et al. J. Neurochem. 110(1):284-294(2009)
Background Reference 2:
Ford, J.W., et al. Curr. Opin. Immunol. 21(1):38-46(2009)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

61-940

List Size:
200 ul

List Price:

$495.00

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