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Western blot analysis of anti-TERF1 Pab in Jurkat cell line lysates (35ug/lane).
Western blot analysis of anti-TERF1 Pab in Jurkat cell line lysates (35ug/lane).

TRF Antibody

CATALOG NUMBER: 61-490

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Hamster
Immunogen:
This TRF (TERF1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 337-366 amino acids from the C-terminal region of human TRF (TERF1).
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
50 kDa
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
TERF1
Additional Names:
Telomeric repeat-binding factor 1, NIMA-interacting protein 2, TTAGGG repeat-binding factor 1, Telomeric protein Pin2/TRF1, TERF1, PIN2, TRBF1, TRF, TRF1
Protein Accession Number:
P54274
Protein Gi Number:
206729904
Ncbi Gene Id Number:
7013
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
TERF1 is a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus.
Background Reference 1:
Kim,M.K., J. Biol. Chem. 283 (20), 14144-14152 (2008)
Background Reference 2:
Etheridge,K.T., J. Biol. Chem. 283 (11), 6935-6941 (2008)
Background Reference 3:
Muramatsu,Y., Exp. Cell Res. 314 (5), 1115-1124 (2008)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

61-490

List Size:
400 ul

List Price:

$495.00

Datasheet
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