TRIM22 Antibody

CATALOG NUMBER: 60-591

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This TRIM22 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 67-96 amino acids from the N-terminal region of human TRIM22.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
57 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
TRIM22
Additional Names:
E3 ubiquitin-protein ligase TRIM22, 632-, 50 kDa-stimulated trans-acting factor, RING finger protein 94, Staf-50, Tripartite motif-containing protein 22, TRIM22, RNF94, STAF50
Protein Accession Number:
Q8IYM9
Protein Gi Number:
47606181
Ncbi Gene Id Number:
10346
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is a member of thetripartite motif (TRIM) family. The TRIM motif includes threezinc-binding domains, a RING, a B-box type 1 and a B-box type 2,and a coiled-coil region. This protein localizes to the cytoplasmand its expression is induced by interferon. The proteindown-regulates transcription from the HIV-1 LTR promoter region,suggesting that function of this protein may be to mediateinterferon's antiviral effects.
Background Reference 1:
Kajaste-Rudnitski, A., et al. Amino Acids 39(1):1-9(2010)
Background Reference 2:
Petersson, J., et al. Exp. Cell Res. 316(4):568-579(2010)
Background Reference 3:
Ovsyannikova, I.G., et al. Hum. Genet. 127(2):207-221(2010)
Background Reference 4:
Ovsyannikova, I.G., et al. J. Infect. Dis. 201(2):207-213(2010)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-591

List Size:
400 ul

List Price:

$495.00

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