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Western blot analysis of extracts from Jurkat cells treated with starved using Phospho-Trk A (Tyr680/Tyr681) Antibody. The lane on the right is treated with the antigen-specific peptide.
Western blot analysis of extracts from Jurkat cells treated with starved using Phospho-Trk A (Tyr680/Tyr681) Antibody. The lane on the right is treated with the antigen-specific peptide.

Trk A (phospho Tyr680/681) Antibody

CATALOG NUMBER: 79-956

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Trk A (phospho Tyr680/681) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 680/tyrosine 681 (T-D-Y (p)-Y (p)-R-V) derived from Human Trk A.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
Western Blot: 1:500~1:1000
Specificity:
The antibody detects endogenous level of Trk A only when phosphorylated at tyrosine 680/tyrosine 681.
Predicted Molecular Weight:
87 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Isotype:
IgG
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
NTRK1
Additional Names:
High affinity nerve growth factor receptor precursor, NTRK1, Slow nerve growth, TRK, Trk-A
Protein Accession Number:
NP_001007793.1
Protein Gi Number:
56118210
Ncbi Gene Id Number:
4914
Background:
Required for high-affinity binding to nerve growth factor (NGF), neurotrophin-3 and neurotrophin-4/5 but not brain-derived neurotrophic factor (BDNF). Known substrates for the Trk receptors are SHC1, PI 3-kinase, and PLC-gamma-1. Has a crucial role in the development and function of the nociceptive reception system as well as establishment of thermal regulation via sweating. Activates ERK1 by either SHC1- or PLC-gamma-1-dependent signaling pathway.
Background Reference 1:
Liu HY, et al. (2005) J Biol Chem 280, 19461-71
Background Reference 2:
Wahab NA, Weston BS, Mason RM (2005) J Am Soc Nephrol 16, 340-51
Background Reference 3:
Marsh HN, et al. (2003) J Cell Biol 163, 999-1010

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-956

List Size:
0.1 mg

List Price:

$355.00

Out of stock

Datasheet
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