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Trk B (phospho Tyr706/Tyr707) Antibody

CATALOG NUMBER: 79-869

Clonality:
Polyclonal
Tested Applications:
IHC
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Trk B (phospho Tyr706/Tyr707) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 706/tyrosine 707 (T-D-Y (p)-Y (p)-R-V)derived from Human Trk B.
Conjugate:
Unconjugated
Tested Applications:
IHC
Specificity:
The antibody detects endogenous levels of Trk B only when phosphorylated at tyrosine 706 and tyrosine 707.
Predicted Molecular Weight:
91 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Isotype:
IgG
physical-state:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
NTRK2
Additional Names:
Trk-B, NTRK2, GP145-TrkB
Protein Accession Number:
NP_001018074.1
Protein Gi Number:
2497560
Ncbi Gene Id Number:
4915
Background:
Receptor for brain-derived neurotrophic factor (BDNF), neurotrophin-3 and neurotrophin-4/5 but not nerve growth factor (NGF). Involved in the development and/or maintenance of the nervous system. This is a tyrosine-protein kinase receptor. Known substrates for the TRK receptors are SHC1, PI-3 kinase, and PLC-gamma-1.
Background Reference 1:
Nakagawara A., Genomics 25:538-546(1995).
Background Reference 2:
Shelton D.L., J. Neurosci. 15:477-491(1995).
Background Reference 3:
Stoilov P., Biochem. Biophys. Res. Commun. 290:1054-1065(2002).

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-869

List Size:
0.1 mg

List Price:

$376.00

Datasheet
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