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Western blot analysis of lysed extracts from mouse brain tissue using TrkB (Phospho-Tyr705).
Western blot analysis of lysed extracts from mouse brain tissue using TrkB (Phospho-Tyr705).

TrkB (phospho Tyr705) Antibody

CATALOG NUMBER: 79-502

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
TrkB (Phospho-Tyr705) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 705 (T-D-Y P-Y-R) derived from Human TrkB.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
Western Blot: 1:500~1:1000
Specificity:
This antibody detects endogenous level of TrkB only when phosphorylated at tyrosine 705.
Predicted Molecular Weight:
140 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
NTRK2
Additional Names:
TRKB, trk-B, GP145-TrkB, P53, BDNF/NT-3 growth factors receptor precursor, EC 2.7.10.1, GP145-TrkB/GP95-TrkB, NTRK2
Protein Accession Number:
NP_001007098.1
Protein Gi Number:
55956790
Ncbi Gene Id Number:
4915
Background:
Receptor for brain-derived neurotrophic factor (BDNF), neurotrophin-3 and neurotrophin-4/5 but not nerve growth factor (NGF). Involved in the development and/or maintenance of the nervous system. This is a tyrosine-protein kinase receptor. Known substrates for the TRK receptors are SHC1, PI-3 kinase, and PLC γ1.
Background Reference 1:
Woronowicz A, et al. Glycobiology. 2007 Jan;17 (1): 10-24. Mojsilovic-Petrovic J, et al. J Neurosci. 2006 Sep 6;26 (36): 9250-63. Lewis MA, et al. Mol Pharmacol. 2006 Apr;69 (4): 1396-404. Cai D, et al. Physiol Genomics. 2006 Feb 14;24 (3): 191-7.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-502

List Size:
0.1 mg

List Price:

$376.00

Datasheet
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