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Western blot analysis of lysed extracts from A549 and mouse brain tissue using TRPC6 Antibody.
Western blot analysis of lysed extracts from A549 and mouse brain tissue using TRPC6 Antibody.

TRPC6 Antibody

CATALOG NUMBER: 79-629

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
TRPC6 antibodypeptide Corresponding to the amino terminal sequence derived from mouse TRPC6.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
Western Blot: 1:500~1:1000
Specificity:
This antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Predicted Molecular Weight:
100 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
TRPC6
Additional Names:
TRP6, FSGS2, TRP6, FLJ11098
Protein Accession Number:
NP_004612.2
Protein Gi Number:
5730102
Ncbi Gene Id Number:
7225
Background:
The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2).
Background Reference 1:
Koichiro Kuwahara et al. (2006) J Clin Invest. 116 (12): 3114–3126. Mark Estacion et al. (2006) J Physiol. 2006, 572 (Pt 2): 359–377. Maria A et al. (2006) Proc Natl Acad Sci U S A. 103 (44): 16586–16591.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-629

List Size:
0.1 mg

List Price:

$370.00

Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

$35 Dry Ice Shipment fee may be required on some items.

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