TRPM4 Antibody

CATALOG NUMBER: 58-239

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This TRPM4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1121-1149 amino acids from the C-terminal region of human TRPM4.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
134 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
TRPM4
Additional Names:
Transient receptor potential cation channel subfamily M member 4, hTRPM4, Calcium-activated non-selective cation channel 1, Long transient receptor potential channel 4, LTrpC-4, LTrpC4, Melastatin-4, TRPM4, LTRPC4
Protein Accession Number:
Q8TD43
Protein Gi Number:
74715868
Ncbi Gene Id Number:
54795
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is a calcium-activatednonselective ion channel that mediates transport of monovalentcations across membranes, thereby depolarizing the membrane. Theactivity of the encoded protein increases with increasingintracellular calcium concentration, but this channel does nottransport calcium. Two transcript variants encoding differentisoforms have been found for this gene.
Background Reference 1:
Liu, H., et al. Circ Cardiovasc Genet 3(4):374-385(2010)
Background Reference 2:
Yoo, J.C., et al. Biochem. Biophys. Res. Commun. 391(1):806-811(2010)
Background Reference 3:
Kruse, M., et al. J. Clin. Invest. 119(9):2737-2744(2009)
Background Reference 4:
Marigo, V., et al. Mol. Cell. Endocrinol. 299(2):194-203(2009)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-239

List Size:
400 ul

List Price:

$495.00

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