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Western blot analysis in CEM cell line lysates (35ug/lane).
TRPM6(CHAK2) Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TRPM6 Antibody (CHAK2) for immunohistochemistry.
Western blot analysis in CEM cell line lysates (35ug/lane).

TRPM6 Antibody

CATALOG NUMBER: 63-369

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This TRPM6 (CHAK2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 317-348 amino acids from the Central region of human TRPM6 (CHAK2).
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
232 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
TRPM6
Additional Names:
Transient receptor potential cation channel subfamily M member 6, Channel kinase 2, Melastatin-related TRP cation channel 6, TRPM6, CHAK2
Protein Accession Number:
Q9BX84
Protein Gi Number:
56404951
Ncbi Gene Id Number:
140803
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
CHAK2 is a member of the ion channel proteins. It regulates the calcium concentration in cells, which is imperative for such functions as muscle contractions and neuronal firing. It is also upregulated in certain forms of cancer and could play a role in diabetes.
Background Reference 1:
Blume-Jensen P, et al. Nature 2001. 411: 355.
Background Reference 2:
Cantrell D, J. Cell Sci. 2001. 114: 1439.
Background Reference 3:
JhiangOncogene 2000. 19: 5590.
Background Reference 4:
Manning G, et al. Science 2002. 298: 1912.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

63-369

List Size:
400 ul

List Price:

$495.00

Datasheet
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