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Western blot analysis in Hela cell line lysates (35ug/lane).
Western blot analysis in Hela cell line lysates (35ug/lane).

TSEN2 Antibody

CATALOG NUMBER: 60-318

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This TSEN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-43 amino acids from the N-terminal region of human TSEN2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
53 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
TSEN2
Additional Names:
tRNA-splicing endonuclease subunit Sen2, tRNA-intron endonuclease Sen2, HsSen2, TSEN2, SEN2
Protein Accession Number:
Q8NCE0
Protein Gi Number:
50428914
Ncbi Gene Id Number:
80746
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes one of the subunits of the tRNA splicingendonuclease. This endonuclease catalyzes the first step in RNAsplicing which is the removal of introns. Mutations in this genehave been associated with pontocerebellar hypoplasia type 2. Apseudogene has been identified on chromosome 4. Multiple transcriptvariants encoding different isoforms have been found for this gene.
Background Reference 1:
Weitzer, S., et al. Nature 447(7141):222-226(2007)
Background Reference 2:
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Background Reference 3:
Ballif, B.A., et al. Mol. Cell Proteomics 3(11):1093-1101(2004)
Background Reference 4:
Paushkin, S.V., et al. Cell 117(3):311-321(2004)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-318

List Size:
400 ul

List Price:

$495.00

Datasheet
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