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Antibody is used in Western blot to detect TSG101 in ZR75-1 cell lysate
Antibody is used in Western blot to detect TSG101 in ZR75-1 cell lysate

TSG101 Antibody

CATALOG NUMBER: 61-117

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This TSG101 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 340-370 amino acids from the C-terminal region of human TSG101.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
44 kDa
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
TSG101
Additional Names:
Tumor susceptibility gene 101 protein, ESCRT-I complex subunit TSG101, TSG101
Protein Accession Number:
Q99816
Protein Gi Number:
9789790
Ncbi Gene Id Number:
7251
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
TSG101 belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression.
Background Reference 1:
Favre, M., et al., J. Acquir. Immune Defic. Syndr. 34(2):127-133 (2003).
Background Reference 2:
Lu, Q., et al., Proc. Natl. Acad. Sci. U.S.A. 100(13):7626-7631 (2003).
Background Reference 3:
Goila-Gaur, R., et al., J. Virol. 77(11):6507-6519 (2003).
Background Reference 4:
Blanco, S., et al., FEMS Microbiol. Lett. 221(2):151-154 (2003).

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

61-117

List Size:
400 ul

List Price:

$495.00

Datasheet
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