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Cynomolgus TSLP, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
Immobilized Cynomolgus TSLP, His Tag at 5 ug/mL (100 uL/well) can bind Human TSLP R, Fc Tag with a linear range of 2-31 ng/mL (QC tested).
Immobilized Cynomolgus TSLP, His Tag at 5 ug/mL (100 uL/well) can bind Monoclonal Anti-Human TSLP Antibody, Human IgG2 with a linear range of 1-16 ng/mL (Routinely tested).
Cynomolgus TSLP, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.

TSLP Recombinant Protein

CATALOG NUMBER: 11-234

Tested Applications:
ELISA, WB
Specifications
source-species:
HEK293 cells
Species:
Cynomolgus monkey
source-species:
HEK293 cells
Recombinant Protein Sequence:
Tyr 29 - Gln 159
Fusion Tag:
His Tag
Tested Applications:
ELISA, WB
Application Note:
This protein carries a polyhistidine tag at the C-terminus.This protein contains a furin convertase cleavage site, 127-RRKR-130, and will be processed into N and C-terminal fragment with calculated MW of 11.7 kDa and 5.4 kDa respectively. The protein mig
Predicted Molecular Weight:
11.7 kDa and 5.4 kDa
Purity:
>90% as determined by SDS-PAGE.
physical-state:
Lyophilized
Buffer:
PBS, pH7.4
Storage Conditions:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Ncbi Official Symbol:
TSLP
Additional Names:
TSLP
Protein Accession Number:
XP_005557555.1
Ncbi Gene Id Number:
102119254
Background:
Thymic stromal lymphopoietin (TSLP) is an epithelial cell-derived cytokine involved in the pathology of inflammatory skin diseases, and is widely expressed by epithelial cells. Human TSLP cDNA encodes a 159 amino acid (aa) residue precursor protein with a 28 aa signal sequence (4, 5). Human TSLP has been shown to developing nondeletional central tolerance, amplifying epithelium-induced class switching, inducing atopic diseases and maintaining intestinal noninflammatory environment. Among diverse cells responding to Human TSLP, CD11c+ dendritic cells are the most obviously characterized target cells.
Background Reference 1:
Segawa R., et al., 2017, J. Dermatol. Sci. S0923-1811:31012-31015.
Background Reference 2:
Wang J., et al., 2008, Cell. Mol. Immunol. 5:99-106.
Background Reference 3:
Soumelis V., et al., 2002, Nat. Immunol. 3:673-680.

FOR RESEARCH USE ONLY

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Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

11-234

List Size:
0.1 mg

List Price:

$577.00

Datasheet
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