Start Your Project

🛍️Explore our Promotions page to discover current deals, limited-time offers, and more!🌟

Western blot analysis in Ramos cell line lysates (35ug/lane).
Western blot analysis in Ramos cell line lysates (35ug/lane).

TTL Antibody

CATALOG NUMBER: 58-579

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Pig, Rat
Immunogen:
This TTL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 232-263 amino acids from the C-terminal region of human TTL.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
43 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
TTL
Additional Names:
Tubulin--tyrosine ligase, TTL, TTL
Protein Accession Number:
Q8NG68
Protein Gi Number:
47117358
Ncbi Gene Id Number:
150465
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
TTL is a cytosolic enzyme involved in theposttranslational modification of alpha-tubulin (see MIM 602529).Alpha-tubulin within assembled microtubules is detyrosinated overtime at the C terminus. After microtubule disassembly, TTL restoresthe tyrosine residues and consequently participates in a cycle oftubulin detyrosination and tyrosination (Erck et al., 2003 [PubMed14571137]).
Background Reference 1:
Dick, D.M., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (6), 1179-1188 (2010) :
Background Reference 2:
Erck, C., et al. Cytogenet. Genome Res. 101(1):47-53(2003)
Background Reference 3:
Mialhe, A., et al. Cancer Res. 61(13):5024-5027(2001)
Background Reference 4:
Ersfeld, K., et al. J. Cell Biol. 120(3):725-732(1993)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-579

List Size:
400 ul

List Price:

$495.00

Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

$35 Dry Ice Shipment fee may be required on some items.

Note: Online orders only accepted for shipment within the USA. Click here for the list of international distributors.

Customize your order

Bulk Pricing Available

Custom Formulations: azide free, endotoxin testing & endotoxin removal.

Pair your antibody with a Lysate, Peptide, Control, & /OR Secondary Antibody.

Contact our Customer Care Team for more information

Custom Antibody Services

Speak to one of our custom antibody specialists to discuss your next custom antibody project.

New & Featured Products

HIV-1 p24 Antibody [9D2F6] (HRP)
HIV-1 p24 Antibody [9D2F6] (HRP)

CATALOG NUMBER: PM-7369-HRP

HIV-1 p24 Antibody [9D2F6] (biotin)
HIV-1 p24 Antibody [9D2F6] (biotin)

CATALOG NUMBER: PM-7369-biotin

HIV-1 p24 Antibody [9D2F6]
HIV-1 p24 Antibody [9D2F6]

CATALOG NUMBER: PM-7369