TULP3 Antibody

CATALOG NUMBER: 60-269

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This TULP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 374-400 amino acids from the C-terminal region of human TULP3.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
50 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
TULP3
Additional Names:
Tubby-related protein 3, Tubby-like protein 3, TULP3, TUBL3
Protein Accession Number:
O75386
Ncbi Gene Id Number:
7289
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a member of the tubby gene family ofbipartite transcription factors. Members of this family have beenidentified in plants, vertebrates, and invertebrates, and theyshare a conserved N-terminal transcription activation region and aconserved C-terminal DNA and phosphatidylinositol-phosphate bindingregion. The encoded protein binds to phosphoinositides in theplasma membrane via its C-terminal region and probably functions asa membrane-bound transcription regulator that translocates to thenucleus in response to phosphoinositide hydrolysis, for instance,induced by G-protein-coupled-receptor signaling. It plays animportant role in neuronal development and function. Two transcriptvariants encoding distinct isoforms have been identified for thisgene.
Background Reference 1:
Jugessur, A., et al. PLoS ONE(7), E11493 (2010) :
Background Reference 2:
Ikeda, A., et al. J. Cell. Sci. 115 (PT 1), 9-14 (2002) :
Background Reference 3:
Santagata, S., et al. Science 292(5524):2041-2050(2001)
Background Reference 4:
Ikeda, S., et al. Invest. Ophthalmol. Vis. Sci. 40(11):2706-2712(1999)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-269

List Size:
400 ul

List Price:

$495.00

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