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Western blot analysis of lysed extracts from A549, HeLa and 3T3 cells using Twist2 Antibody.
Western blot analysis of lysed extracts from A549, HeLa and 3T3 cells using Twist2 Antibody.

Twist2 Antibody

CATALOG NUMBER: 79-768

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Twist2 antibody was raised against a peptide sequence around aa.26~30 (P-K-R-F-G) derived from Human Twist2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
Western Blot: 1:500~1:1000
Specificity:
This antibody detects endogenous level of total Twist2 protein.
Predicted Molecular Weight:
18 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
TWIST2
Additional Names:
FFDD3, DERMO1, SETLSS, bHLHa39, MGC117334
Protein Accession Number:
NP_476527.1
Protein Gi Number:
17981708
Ncbi Gene Id Number:
117581
Background:
Binds to the E-box consensus sequence 5'-CANNTG-3' as a heterodimer and inhibits transcriptional activation by MYOD1, MYOG, MEF2A and MEF2C. Also represses expression of proinflammatory cytokines such as TNFA and IL1B. Involved in postnatal glycogen storage and energy metabolism. Inhibits the premature or ectopic differentiation of preosteoblast cells during osteogenesis, possibly by changing the internal signal transduction response of osteoblasts to external growth factors.
Background Reference 1:
Lee M. S., Lowe G., Flanagan S., Kuchler K., Glackin C. A. Bone 27:591-602 (2000)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-768

List Size:
0.1 mg

List Price:

$370.00

Datasheet
Shipping Info

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