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Western Blot at 1:2000 dilution + PC-3 whole cell lysate Lysates/proteins at 20 ug per lane.
Western Blot at 1:2000 dilution + PC-3 whole cell lysate Lysates/proteins at 20 ug per lane.

TXNRD1 Antibody

CATALOG NUMBER: 61-353

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Pig
Immunogen:
This TXNRD1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 271-305 amino acids from the Central region of human TXNRD1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:2000
Predicted Molecular Weight:
71 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
TXNRD1
Additional Names:
Thioredoxin reductase 1, cytoplasmic, TR, 1.8.1.9, Gene associated with retinoic and interferon-induced mortality 12 protein, GRIM-12, Gene associated with retinoic and IFN-induced mortality 12 protein, KM-102-derived reductase-like factor, Thioredoxin reductase TR1, TXNRD1, GRIM12, KDRF
Protein Accession Number:
Q16881
Protein Gi Number:
172046253
Ncbi Gene Id Number:
7296
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid.
Background Reference 1:
Gasdaska P.Y.,et al.FEBS Lett. 373:5-9(1995).
Background Reference 2:
Koishi R.,et al.J. Biol. Chem. 272:2570-2577(1997).
Background Reference 3:
Hofman E.R.,et al.Mol. Cell. Biol. 18:6493-6504(1998).
Background Reference 4:
Rundloef A.-K.,et al.Free Radic. Biol. Med. 36:641-656(2004).

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

61-353

List Size:
200 ul

List Price:

$495.00

Datasheet
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