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Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).
Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).

TXNRD3 Antibody

CATALOG NUMBER: 60-626

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This TXNRD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 304-333 amino acids from the Central region of human TXNRD3.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
71 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
TXNRD3
Additional Names:
Thioredoxin reductase 3, Thioredoxin and glutathione reductase, Thioredoxin reductase TR2, TXNRD3 {ECO:0000312, EMBL:AAH500321}
Protein Accession Number:
Q86VQ6
Protein Gi Number:
510120859
Ncbi Gene Id Number:
114112
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a member of the family of pyridinenucleotide oxidoreductases. This protein catalyzes the reduction ofthioredoxin, and is implicated in the defense against oxidativestress. It contains a selenocysteine (Sec) residue (which isessential for catalytic activity), encoded by a UGA codon, at thepenultimate C-terminal position. The 3' UTR of Sec-containing geneshave a common stem-loop structure, the sec insertion sequence(SECIS), which is necessary for the recognition of UGA as a Seccodon rather than as a stop signal. Alternatively splicedtranscript variants encoding different isoforms have been found forthis gene.
Background Reference 1:
Gerashchenko, M.V., et al. J. Biol. Chem. 285(7):4595-4602(2010)
Background Reference 2:
Starr, J.M., et al. Mech. Ageing Dev. 129(12):745-751(2008)
Background Reference 3:
Harris, S.E., et al. BMC Genet. 8, 43 (2007) :
Background Reference 4:
Kryukov, G.V., et al. Science 300(5624):1439-1443(2003)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-626

List Size:
400 ul

List Price:

$469.00

Out of stock

Datasheet
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