UBA6 Antibody

CATALOG NUMBER: 58-782

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This UBA6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 861-889 amino acids from the C-terminal region of human UBA6.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
118 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
UBA6
Additional Names:
Ubiquitin-like modifier-activating enzyme 6, Ubiquitin-activating enzyme 6, Monocyte protein 4, MOP-4, Ubiquitin-activating enzyme E1-like protein 2, E1-L2, UBA6, MOP4, UBE1L2
Protein Accession Number:
A0AVT1
Ncbi Gene Id Number:
55236
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Modification of proteins with ubiquitin (UBB; MIM 191339)or ubiquitin-like proteins controls many signaling networks andrequires a ubiquitin-activating enzyme (E1), a ubiquitinconjugating enzyme (E2), and a ubiquitin protein ligase (E3).UBE1L2 is an E1 enzyme that initiates the activation andconjugation of ubiquitin-like proteins (Jin et al., 2007 [PubMed17597759]).
Background Reference 1:
Groettrup, M., et al. Trends Biochem. Sci. 33(5):230-237(2008)
Background Reference 2:
Chiu, Y.H., et al. Mol. Cell 27(6):1014-1023(2007)
Background Reference 3:
Pelzer, C., et al. J. Biol. Chem. 282(32):23010-23014(2007)
Background Reference 4:
Jin, J., et al. Nature 447(7148):1135-1138(2007)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-782

List Size:
400 ul

List Price:

$495.00

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