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Western blot analysis in mouse heart tissue lysates (35ug/lane).
Western blot analysis in mouse heart tissue lysates (35ug/lane).

UBASH3A Antibody

CATALOG NUMBER: 60-363

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Mouse
Immunogen:
This UBASH3A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 313-340 amino acids from the Central region of human UBASH3A.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
74 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
UBASH3A
Additional Names:
Ubiquitin-associated and SH3 domain-containing protein A, Cbl-interacting protein 4, CLIP4, Suppressor of T-cell receptor signaling 2, STS-2, T-cell ubiquitin ligand 1, TULA-1, UBASH3A, STS2
Protein Accession Number:
P57075
Protein Gi Number:
10720330
Ncbi Gene Id Number:
53347
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
UBASH3A interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors, EGFR and PDGFRB, on the cell surface.
Background Reference 1:
Hinks, A., et al. Ann. Rheum. Dis. (2010) In press :
Background Reference 2:
Stahl, E.A., et al. Nat. Genet. 42(6):508-514(2010)
Background Reference 3:
Jin, Y., et al. N. Engl. J. Med. 362(18):1686-1697(2010)
Background Reference 4:
Barrett, J.C., et al. Nat. Genet. 41(6):703-707(2009)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-363

List Size:
400 ul

List Price:

$495.00

Datasheet
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