UBE2R2 Antibody

CATALOG NUMBER: 60-700

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rabbit
Immunogen:
This UBE2R2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 141-169 amino acids from the Central region of human UBE2R2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
27 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
UBE2R2
Additional Names:
Ubiquitin-conjugating enzyme E2 R2, Ubiquitin carrier protein R2, Ubiquitin-conjugating enzyme E2-CDC34B, Ubiquitin-protein ligase R2, UBE2R2, CDC34B, UBC3B
Protein Accession Number:
Q712K3
Protein Gi Number:
74749761
Ncbi Gene Id Number:
54926
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Protein kinase CK2 is a ubiquitous and pleiotropic Ser/Thrprotein kinase involved in cell growth and transformation. Thisgene encodes a protein similar to the E2 ubiquitin conjugatingenzyme UBC3/CDC34. Studies suggest that CK2-dependentphosphorylation of this ubiquitin-conjugating enzyme functions byregulating beta-TrCP substrate recognition and induces itsinteraction with beta-TrCP, enhancing beta-catenin degradation.
Background Reference 1:
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 2:
Yoshida, T., et al. Int. J. Mol. Med. 25(4):649-656(2010)
Background Reference 3:
Oguri, M., et al. Am. J. Hypertens. 23(1):70-77(2010)
Background Reference 4:
Ferreira, M.A., et al. Nat. Genet. 40(9):1056-1058(2008)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-700

List Size:
400 ul

List Price:

$495.00

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