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Western blot analysis in mouse liver tissue lysates (35ug/lane).
Western blot analysis in mouse liver tissue lysates (35ug/lane).

UBR1 Antibody

CATALOG NUMBER: 60-918

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Mouse
Immunogen:
This UBR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 245-274 amino acids from the N-terminal region of human UBR1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
200 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
UBR1
Additional Names:
E3 ubiquitin-protein ligase UBR1, 632-, N-recognin-1, Ubiquitin-protein ligase E3-alpha-1, Ubiquitin-protein ligase E3-alpha-I, UBR1
Protein Accession Number:
Q8IWV7
Protein Gi Number:
73622071
Ncbi Gene Id Number:
197131
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The N-end rule pathway is one proteolytic pathway of theubiquitin system. The recognition component of this pathway,encoded by this gene, binds to a destabilizing N-terminal residueof a substrate protein and participates in the formation of asubstrate-linked multiubiquitin chain. This leads to the eventualdegradation of the substrate protein. The protein described in thisrecord has a RING-type zinc finger and a UBR-type zinc finger.Mutations in this gene have been associated with Johanson-Blizzardsyndrome.
Background Reference 1:
Elting, M., et al. Am. J. Med. Genet.146A (23), 3058-3061 (2008) :
Background Reference 2:
Alkhouri, N., et al. World J. Gastroenterol. 14(44):6863-6866(2008)
Background Reference 3:
Yamaguchi, Y., et al. BMC Med. Genet. 9, 22 (2008) :
Background Reference 4:
Schmidt, R.L., et al. Cancer Res. 67(24):11798-11810(2007)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-918

List Size:
400 ul

List Price:

$495.00

Datasheet
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