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Western blot analysis in SK-BR-3 cell line lysates (35ug/lane).
Western blot analysis in SK-BR-3 cell line lysates (35ug/lane).

UGT2B7 Antibody

CATALOG NUMBER: 59-716

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This UGT2B7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 97-126 amino acids from the N-terminal region of human UGT2B7.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
61 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
UGT2B7
Additional Names:
UDP-glucuronosyltransferase 2B7, UDPGT 2B7,4-catechol estrogen-specific UDPGT, UDP-glucuronosyltransferase 2B9, UDPGT 2B9, UDPGTh-2, UGT2B7, UGTB2B9
Protein Accession Number:
P16662
Protein Gi Number:
136727
Ncbi Gene Id Number:
7364
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The UGTs (EC 2.4.1.17) serve a major role in theconjugation and subsequent elimination of potentially toxicxenobiotics and endogenous compounds. UGT2B7 has unique specificityfor 3,4-catechol estrogens and estriol, suggesting that it may playan important role in regulating the level and activity of thesepotent estrogen metabolites. Its subcellular location is themicrosome.
Background Reference 1:
Joy, M.S., et al. Eur. J. Clin. Pharmacol. 66(11):1119-1130(2010)
Background Reference 2:
Canzian, F., et al. Hum. Mol. Genet. 19(19):3873-3884(2010)
Background Reference 3:
Hu, M., et al. Pharmacogenet. Genomics 20(10):634-637(2010)
Background Reference 4:
Woillard, J.B., et al. BrClin Pharmacol 69(6):675-683(2010)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-716

List Size:
400 ul

List Price:

$495.00

Datasheet
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