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Western blot analysis in mouse stomach tissue lysates (35ug/lane).
Western blot analysis in mouse stomach tissue lysates (35ug/lane).

UNC13B Antibody

CATALOG NUMBER: 56-860

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Mouse
Immunogen:
This UNC13B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 263-292 amino acids from the N-terminal region of human UNC13B.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
181 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
UNC13B
Additional Names:
Protein unc-13 homolog B, Munc13-2, munc13, UNC13B, UNC13
Protein Accession Number:
O14795
Ncbi Gene Id Number:
10497
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene is expressed in the kidney cortical epithelialcells and is upregulated by hyperglycemia. The encoded proteinshares a high level of similarity to the rat homolog, and contains3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemiaincreases the levels of diacylglycerol, which has been shown toinduce apoptosis in cells transfected with this gene and thuscontribute to the renal cell complications of hyperglycemia.Studies in other species also indicate a role for this protein inthe priming step of synaptic vesicle exocytosis. [provided byRefSeq].
Background Reference 1:
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 2:
Goldenberg, N.M., et al. Am. J. Physiol., Cell Physiol. 297 (4), C1053-C1058 (2009) :
Background Reference 3:
Dimova, K., et al. Biochemistry 48(25):5908-5921(2009)
Background Reference 4:
Tregouet, D.A., et al. Diabetes 57(10):2843-2850(2008)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

56-860

List Size:
400 ul

List Price:

$495.00

Datasheet
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