UNC45A Antibody

CATALOG NUMBER: 56-678

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This UNC45A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 146-174 amino acids from the N-terminal region of human UNC45A.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
103 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
UNC45A
Additional Names:
Protein unc-45 homolog A, Unc-45A, GCUNC-45, Smooth muscle cell-associated protein 1, SMAP-1, UNC45A, SMAP1
Protein Accession Number:
Q9H3U1
Protein Gi Number:
74761419
Ncbi Gene Id Number:
55898
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
UNC45A plays a role in cell proliferation and myoblastfusion, binds progesterone receptor (PGR; MIM 607311) and HSP90(HSPCA; MIM 140571), and acts as a regulator of the progesteronereceptor chaperoning pathway (Price et al., 2002 [PubMed 12356907];Chadli et al., 2006 [PubMed 16478993]).
Background Reference 1:
Chadli, A., et al. J. Biol. Chem. 283(15):9509-9512(2008)
Background Reference 2:
Bazzaro, M., et al. Am. J. Pathol. 171(5):1640-1649(2007)
Background Reference 3:
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Background Reference 4:
Olsen, J.V., et al. Cell 127(3):635-648(2006)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

56-678

List Size:
400 ul

List Price:

$495.00

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