UNC5D Antibody

CATALOG NUMBER: 56-833

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This UNC5D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 483-511 amino acids from the Central region of human UNC5D.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
106 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
UNC5D
Additional Names:
Netrin receptor UNC5D, Protein unc-5 homolog 4, Protein unc-5 homolog D, UNC5D, KIAA1777, UNC5H4
Protein Accession Number:
Q6UXZ4
Protein Gi Number:
54036576
Ncbi Gene Id Number:
137970
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
UNC5D is receptor for netrin. May be involved in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand (By similarity).
Background Reference 1:
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 2:
Wang, H., et al. Biochem. Biophys. Res. Commun. 370(4):594-598(2008)
Background Reference 3:
Choy, K.W., et al. Physiol. Genomics 25(1):9-15(2006)
Background Reference 4:
Zhong, Y., et al. Cereb. Cortex 14(10):1144-1152(2004)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

56-833

List Size:
400 ul

List Price:

$495.00

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