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Western blot analysis in MDA-MB435 cell line lysates (35ug/lane).
Western blot analysis in MDA-MB435 cell line lysates (35ug/lane).

UNC84B Antibody

CATALOG NUMBER: 56-427

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This UNC84B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 237-265 amino acids from the Central region of human UNC84B.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
80 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SUN2
Additional Names:
SUN domain-containing protein 2, Protein unc-84 homolog B, Rab5-interacting protein, Rab5IP, Sad1/unc-84 protein-like 2, SUN2, FRIGG, KIAA0668, RAB5IP, UNC84B
Protein Accession Number:
Q9UH99
Protein Gi Number:
29337242
Ncbi Gene Id Number:
25777
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
SUN1 (MIM 607723) and SUN2 are inner nuclear membrane(INM) proteins that play a major role in nuclear-cytoplasmicconnection by formation of a 'bridge' across the nuclear envelope,known as the LINC complex, via interaction with the conservedluminal KASH domain of nesprins (e.g., SYNE1; MIM 608441) locatedin the outer nuclear membrane (ONM). The LINC complex provides adirect connection between the nuclear lamina and the cytoskeleton,which contributes to nuclear positioning and cellular rigidity(summary by Haque et al., 2010 [PubMed 19933576]).[supplied byOMIM].
Background Reference 1:
Turgay, Y., et al. EMBO J. 29(14):2262-2275(2010)
Background Reference 2:
Haque, F., et al. J. Biol. Chem. 285(5):3487-3498(2010)
Background Reference 3:
Stewart-Hutchinson, P.J., et al. Exp. Cell Res. 314(8):1892-1905(2008)
Background Reference 4:
Cerhan, J.R., et al. Blood 110(13):4455-4463(2007)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

56-427

List Size:
400 ul

List Price:

$495.00

Datasheet
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