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Immunohistochemistry of paraffin-embedded human liver cancer using UPF1 antibody (15-057) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse brain using UPF1 antibody (15-057) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse heart using UPF1 antibody (15-057) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human liver cancer using UPF1 antibody (15-057) at dilution of 1:100 (40x lens).

UPF1 Antibody

CATALOG NUMBER: 15-057

Clonality:
Polyclonal
Tested Applications:
IHC, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 270-370 of human UPF1 (NP_002902.2).
Conjugate:
Unconjugated
Tested Applications:
IHC, WB
Application Note:
WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
Purification:
Affinity purification
Clonality:
Polyclonal
Isotype:
IgG
physical-state:
Liquid
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Storage Conditions:
Store at -20°C. Avoid freeze / thaw cycles.
Ncbi Official Symbol:
UPF1
Additional Names:
UPF1, FLJ43809, FLJ46894, HUPF1, KIAA0221, NORF1, RENT1, pNORF1, smg-2
Ncbi Gene Id Number:
5976
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. Alternative splicing results in multiple transcript variants.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

15-057

List Size:
100 uL

List Price:

$436.00

Datasheet
Shipping Info

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$35 Dry Ice Shipment fee may be required on some items.

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