UROC1 Antibody

CATALOG NUMBER: 55-667

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This UROC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 402-430 amino acids from the Central region of human UROC1.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
75 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
UROC1
Additional Names:
Urocanate hydratase, Urocanase, Imidazolonepropionate hydrolase, UROC1
Protein Accession Number:
Q96N76
Protein Gi Number:
22256789
Ncbi Gene Id Number:
131669
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes an enzyme involved in histidinecatabolism, metabolizing urocanic acid to formiminoglutamic acid.The gene product is known to protect the skin from ultra violetrays and is contained in human sweat. Deficiency of this geneproduct in the liver is an apparent cause of mental retardation.Multiple transcript variants encoding different isoforms have beenfound for this gene.
Background Reference 1:
Espinos, C., et al. J. Med. Genet. 46(6):407-411(2009)
Background Reference 2:
Yamada, S., et al. Oncogene 23(35):5901-5911(2004)
Background Reference 3:
Retey, J. Arch. Biochem. Biophys. 314(1):1-16(1994)
Background Reference 4:
Kalafatic, Z., et al. Metab. Clin. Exp. 29(11):1013-1019(1980)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

55-667

List Size:
400 ul

List Price:

$495.00

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