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Western blot analysis in CEM cell line lysates (35ug/lane).
Western blot analysis in CEM cell line lysates (35ug/lane).

USP1 Antibody

CATALOG NUMBER: 58-780

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Immunogen:
This USP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 662-690 amino acids from the C-terminal region of human USP1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
88 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
USP1
Additional Names:
Ubiquitin carboxyl-terminal hydrolase 1, Deubiquitinating enzyme 1, hUBP, Ubiquitin thioesterase 1, Ubiquitin-specific-processing protease 1, USP1
Protein Accession Number:
O94782
Ncbi Gene Id Number:
7398
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a member of the ubiquitin-specificprocessing (UBP) family of proteases that is a deubiquitinatingenzyme (DUB) with His and Cys domains. This protein is located inthe cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fusedprecursors and ubiquitinylated proteins. The protein specificallydeubiquitinates a protein in the Fanconi anemia (FA) DNA repairpathway. Alternate transcriptional splice variants have beencharacterized.
Background Reference 1:
Barroso, E., et al. Breast Cancer Res. Treat. 118(3):655-660(2009)
Background Reference 2:
McWilliams, R.R., et al. Cancer Epidemiol. Biomarkers Prev. 18(9):2549-2552(2009)
Background Reference 3:
Cohn, M.A., et al. J. Biol. Chem. 284(8):5343-5351(2009)
Background Reference 4:
Cohn, M.A., et al. Mol. Cell 28(5):786-797(2007)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-780

List Size:
400 ul

List Price:

$495.00

Datasheet
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