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Western blot analysis in SK-BR-3 cell line lysates (35ug/lane).
Western blot analysis in SK-BR-3 cell line lysates (35ug/lane).

USP16 Antibody

CATALOG NUMBER: 58-690

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Monkey
Immunogen:
This USP16 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 132-160 amino acids from the N-terminal region of human USP16.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
94 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
USP16
Additional Names:
Ubiquitin carboxyl-terminal hydrolase 16 {ECO:0000255, HAMAP-Rule:MF_03062}, 341912 {ECO:0000255, HAMAP-Rule:MF_03062}, Deubiquitinating enzyme 16 {ECO:0000255, HAMAP-Rule:MF_03062}, Ubiquitin thioesterase 16 {ECO:0000255, HAMAP-Rule:MF_03062}, Ubiquitin-processing protease UBP-M, Ubiquitin-specific-processing protease 16 {ECO:0000255, HAMAP-Rule:MF_03062}, USP16 {ECO:0000255, HAMAP-Rule:MF_03062}
Protein Accession Number:
Q9Y5T5
Protein Gi Number:
6686071
Ncbi Gene Id Number:
10600
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a deubiquitinating enzyme that isphosphorylated at the onset of mitosis and then dephosphorylated atthe metaphase/anaphase transition. It can deubiquitinate H2A, oneof two major ubiquitinated proteins of chromatin, in vitro and amutant form of the protein was shown to block cell division.Alternate transcriptional splice variants, encoding differentisoforms, have been characterized.
Background Reference 1:
Gelsi-Boyer, V., et al. BMC Cancer 8, 299 (2008) :
Background Reference 2:
Joo, H.Y., et al. Nature 449(7165):1068-1072(2007)
Background Reference 3:
Pai, M.T., et al. J. Mol. Biol. 370(2):290-302(2007)
Background Reference 4:
Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-690

List Size:
400 ul

List Price:

$495.00

Datasheet
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