USP22 Antibody

CATALOG NUMBER: 27-157

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human USP22.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
USP22 antibody can be used for detection of USP22 by ELISA at 1:312500. USP22 antibody can be used for detection of USP22 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. XBL-10407 - Fetal Heart Tissue Lysate
Predicted Molecular Weight:
60 kDa
Purification:
Antibody is purified by peptide affinity chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store USP22 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
USP22
Additional Names:
USP22, KIAA1063, USP3L
Protein Accession Number:
NP_056091
Protein Gi Number:
150010639
Ncbi Gene Id Number:
23326
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
USP22 is a subunit of the SAGA transcriptional cofactor complex. It deubiquitylates histone H2B and is recruited to specific genes by activators like Myc. USP22 is needed for cell cycle progression. It deubiquitylates histone H2A in addition to H2B. Altered mRNA expression is associated with therapy failure and death in patients multiple types of cancer.
Background Reference 1:
Zhang, X.Y., (2008) Mol. Cell 29 (1), 102-111.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

27-157

List Size:
100 ul

List Price:

$519.00

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