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Western blot analysis in mouse brain tissue lysates (35ug/lane).
Western blot analysis in mouse brain tissue lysates (35ug/lane).

VANGL2 Antibody

CATALOG NUMBER: 60-897

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Mouse
Homology:
Predicted species reactivity based on immunogen sequence: Rat
Immunogen:
This VANGL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-65 amino acids from the N-terminal region of human VANGL2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
60 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
VANGL2
Additional Names:
Vang-like protein 2, Loop-tail protein 1 homolog, Strabismus 1, Van Gogh-like protein 2, VANGL2, KIAA1215, STB1
Protein Accession Number:
Q9ULK5
Protein Gi Number:
38258849
Ncbi Gene Id Number:
57216
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Planar cell polarity (PCP) is the term given to globalcell polarization, such as the alignment of mammalian body hairalong the anterior-posterior axis or the orientation of steriociliabundles in the inner ear. VANGL2 is a PCP protein that is involvedin the transmission of directional cues to align either individualcells within an epithelial sheet or multicellular clusters, whichpolarize as a group (Devenport and Fuchs, 2008 [PubMed18849982]).
Background Reference 1:
Lei, Y.P., et al. N. Engl. J. Med. 362(23):2232-2235(2010)
Background Reference 2:
Yates, L.L., et al. Hum. Mol. Genet. 19(11):2251-2267(2010)
Background Reference 3:
Cantrell, V.A., et al. Cancer Lett. 287(1):54-61(2010)
Background Reference 4:
Need, A.C., et al. Hum. Mol. Genet. 18(23):4650-4661(2009)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-897

List Size:
400 ul

List Price:

$495.00

Datasheet
Shipping Info

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