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Western blot analysis of extracts from JK cells using VAV3 (Phospho-Tyr173) Antibody. The lane on the right is treated with the antigen-specific peptide.
Western blot analysis of extracts from JK cells using VAV3 (Phospho-Tyr173) Antibody. The lane on the right is treated with the antigen-specific peptide.

VAV3 (phospho Tyr173) Antibody

CATALOG NUMBER: 79-939

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
VAV3 (phospho Tyr173) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 173 (E-V-Y (p)-E-D) derived from Human VAV3.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
Western Blot: 1:500~1:1000
Specificity:
The antibody detects endogenous levels of VAV3 only when phosphorylated at tyrosine 173.
Predicted Molecular Weight:
100 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Isotype:
IgG
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
VAV3
Additional Names:
VAV3, FLJ40431, Guanine nucleotide exchange factor VAV3
Protein Accession Number:
NP_006104.4
Protein Gi Number:
120432044
Ncbi Gene Id Number:
10451
Background:
This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Background Reference 1:
Trenkle T., Nucleic Acids Res. 26:3883-3891(1998).
Background Reference 2:
Movilla N., Mol. Cell. Biol. 19:7870-7885(1999).

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-939

List Size:
0.1 mg

List Price:

$376.00

Datasheet
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